In the 11/9/2010 Washington Examiner, Paul Howard describes "How Republicans can break Obamacare before they repeal it".
The tactics he describes are good ones, because they highlight the bad economic effects of ObamaCare.
If coupled with more fundamental moral arguments against ObamaCare, including the idea that health care is not a right, then they could be highly effective. Without such arguments, they may not gain sufficient traction amongst the American people.
The most recent election showed that many Americans want to have a debate at the level of fundamental ideas -- such as the proper role of government in people's lives. Let's hope the Republicans are up to that debate.